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Familial Crohn's disease with systemic lupus erythematosus
Y Nishida1, K Murase, R Ashida
1The Second Department of Internal Medicine, Nagasaki University School of Medicine, Japan.
The American Journal of Gastroenterology
|December 22, 1998
Summary
A rare case of Crohn's disease co-occurring with systemic lupus erythematosus (SLE) is presented. Patients with Crohn's disease exhibiting specific symptoms may require evaluation for SLE.
Area of Science:
- Gastroenterology and Immunology
- Autoimmune Diseases
Background:
- Crohn's disease is a chronic inflammatory bowel disease.
- Systemic lupus erythematosus (SLE) is a chronic autoimmune disease.
Observation:
- A young Japanese woman with a family history of Crohn's disease developed perianal abscess.
- She presented with pancytopenia, hematuria, hypocomplementemia, and high autoimmune antibody titers.
Findings:
- The patient was diagnosed with both Crohn's disease and systemic lupus erythematosus (SLE).
- This combination of Crohn's disease and SLE is exceptionally rare.
Implications:
- Patients with Crohn's disease presenting with SLE-like symptoms warrant thorough evaluation for SLE.
- Early diagnosis and management of co-existing autoimmune conditions are crucial for patient outcomes.