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Prognostic value of treadmill exercise testing: a population-based study in Olmsted County, Minnesota
V L Roger1, S J Jacobsen, P A Pellikka
1Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minn 55905, USA.
Circulation
|December 22, 1998
Summary
Treadmill exercise testing (TMET) shows exercise capacity is a strong predictor of mortality and cardiac events in both men and women. Higher exercise capacity significantly reduces risk, highlighting its prognostic value across diverse populations.
Area of Science:
- Cardiology
- Preventive Medicine
- Exercise Physiology
Background:
- Prognostic value of treadmill exercise testing (TMET) is established in select groups.
- Generalizability to broader populations and women remains uncertain.
Purpose of the Study:
- To evaluate the prognostic value of TMET in a general population.
- To determine if predictors and outcomes differ between sexes.
Main Methods:
- Retrospective, population-based cohort study.
- Included 1452 men and 741 women undergoing TMET (1987-1989).
- Follow-up for all-cause mortality and cardiac events.
Main Results:
- Exercise-induced angina, ECG changes, and workload associated with outcomes in both sexes.
- Workload was the strongest predictor after adjustment.
- Higher workload correlated with reduced risk of cardiac events and mortality.
Conclusions:
- Exercise capacity on TMET is a powerful predictor of mortality and cardiac events.
- The protective effect of exercise capacity is consistent in both men and women.