Sarcoidosis presenting as palmar erythema

Area of Science:

• Immunology
• Dermatology
• Pathology

Background:

• Sarcoidosis is a multisystem inflammatory disease of unknown cause.
• It is characterized by non-caseating granulomas in various organs.
• Commonly affects lungs, skin, and lymph nodes.

Observation:

• A patient presented with palmar erythema, a redness of the palms.
• Skin biopsy revealed non-caseating granulomas.
• This presentation is unusual for sarcoidosis.

Findings:

• The patient's palmar erythema was diagnosed as sarcoidosis.
• The condition responded well to systemic corticosteroid treatment.
• This represents a previously unreported clinical manifestation of sarcoidosis.

Implications:

• Highlights the diverse and sometimes atypical presentations of sarcoidosis.
• Suggests palmar erythema as a potential, albeit rare, sign of sarcoidosis.
• Emphasizes the importance of considering sarcoidosis in the differential diagnosis of palmar erythema.