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Lichen planus pemphigoides: two case reports

V J Swale1, M M Black, B S Bhogal

  • 1St. John's Institute of Dermatology, St. Thomas' Hospital, London, UK.

Clinical and Experimental Dermatology
|December 23, 1998
PubMed
Summary
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Lichen planus pemphigoides (LPP) is a rare autoimmune blistering disease. This report highlights the varied clinical presentations of LPP, aiding in diagnosis and management.

Area of Science:

  • Dermatology
  • Immunodermatology
  • Pathology

Background:

  • Lichen planus pemphigoides (LPP) is a rare autoimmune blistering disease.
  • It presents with a combination of lichenoid lesions and bullae.
  • Understanding its diverse manifestations is crucial for accurate diagnosis.

Observation:

  • Two patients with LPP are presented.
  • The cases illustrate the varied clinical appearance of the disease.
  • Both involved and uninvolved skin showed characteristic features.

Findings:

  • LPP exhibits distinct clinical, histological, and immunopathological characteristics.
  • The lichenoid eruption associated with bullae is a hallmark.
  • Diverse presentations can challenge initial diagnosis.

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Implications:

  • Recognizing the spectrum of LPP clinical manifestations improves diagnostic accuracy.
  • Early identification facilitates timely and appropriate patient management.
  • Further research into LPP pathogenesis and treatment is warranted.