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Medication use during the perinatal period

G G Briggs1

  • 1Women's Hospital, Long Beach Memorial Medical Center, CA 90801-1428, USA. jbriggs@memnet.org

Journal of the American Pharmaceutical Association (Washington, D.C. : 1996)
|December 23, 1998
PubMed
Summary

Drug therapy during pregnancy effectively manages common maternal and fetal complications, improving outcomes for mother and baby. Healthcare providers must be knowledgeable about appropriate perinatal pharmacologic treatments.

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Area of Science:

  • Obstetrics and Gynecology
  • Perinatal Medicine
  • Pharmacology

Background:

  • Perinatal drug therapy is frequently necessary for managing maternal and fetal complications.
  • Many conditions that previously caused significant morbidity and mortality can now be controlled with medication.

Purpose of the Study:

  • To outline drug therapies used during pregnancy for common maternal and fetal issues.
  • To identify medications contraindicated for specific perinatal conditions.

Main Methods:

  • Literature search of peer-reviewed obstetric, gynecologic, medical, and pharmacy journals.
  • MEDLINE searches and review of tables of contents from over 1,300 journals.
  • Selection of references based on study design, patient population, and publication date, prioritizing ACOG guidelines.

Main Results:

  • Drug therapy can be beneficial for the mother, fetus, and newborn.
  • Appropriate pharmacologic interventions now control infections, premature rupture of membranes, preterm labor, hypertension, labor pain, and postpartum hemorrhage.
  • Identification of specific agents to avoid in perinatal conditions.

Conclusions:

  • Perinatal drug therapy is essential for managing various pregnancy complications.
  • Knowledge of appropriate pharmacologic treatments is crucial for all healthcare professionals serving pregnant women.
  • Effective drug management reduces severe maternal and fetal morbidity and mortality.

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