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Paranasal sinus mycoses in north India
N K Panda1, S C Sharma, A Chakrabarti
1Department of Otolaryngology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Mycoses
|December 23, 1998
Summary
This study highlights the prevalence and characteristics of fungal infections affecting the paranasal sinuses in North India. Invasive fungal sinusitis requires aggressive treatment, including surgery and antifungal medication, to prevent recurrence and improve outcomes.
Area of Science:
- Otolaryngology
- Mycology
- Infectious Diseases
Background:
- Paranasal sinus mycoses present a significant health concern in North India.
- A retrospective analysis of 178 patients with proven fungal sinusitis was conducted.
Purpose of the Study:
- To analyze the clinical, mycological, and management aspects of paranasal sinus mycoses.
- To categorize disease types and identify risk factors and common presentations.
Main Methods:
- Retrospective analysis of 178 patients.
- Classification based on clinical, radiological, histopathological, and mycological findings.
- Identification of causative fungal species and assessment of treatment outcomes.
Main Results:
- Patients were categorized into allergic (8), non-invasive (92), and invasive (78) types.
- Young men from rural areas were most commonly affected; rhinorrhoea with nasal polyposis and proptosis were frequent symptoms.
- Aspergillus flavus was the most common isolate (79.7%); orbital and intracranial extensions were noted in invasive cases.
Conclusions:
- Non-invasive fungal sinusitis is manageable with surgical debridement and sinus ventilation.
- Invasive fungal sinusitis requires aggressive management with surgery and adjuvant medical therapy, such as itraconazole, for prevention of recurrence.
- Zygomycotic infections had the highest mortality rate (33.3%).