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Radio-imaging for quantitative autoradiography in biology
Y Charon1, P Lanièce, H Tricoire
1Institut de Physique Nucléaire d'Orsay and Groupe Modélisation Interfaces Physique Biologie, Université Diderot, Paris, France. charon@ipno.in2p3.fr
Nuclear Medicine and Biology
|December 24, 1998
Abstract:
We present here an overview of new in vitro and ex vivo radio-imaging systems developed to overcome the limitations of films and emulsions currently used in histological autoradiography experiments. The shortcomings of films for quantitative studies are first introduced. Principles and performances of each family of imagers are discussed and illustrated in various biological contexts. Finally, perspectives of development including nonradioactive labeling techniques are briefly presented.