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Published on: October 6, 2016
Sexual functioning in ambulatory men with HIV/AIDS
Insights
Sexual dysfunction is common in men with HIV, worsening with disease progression. Both low testosterone and psychological factors contribute to sexual health issues in HIV patients.
Area of Science:
- Sexual health
- Endocrinology
- Infectious diseases
Background:
- Sexual functioning is frequently overlooked in human immunodeficiency virus (HIV) patient care.
- Limited data exists on the interplay of hormonal, psychological, medication, and disease stage factors on sexual functioning in HIV-infected individuals.
Purpose of the Study:
- To investigate the relationship between hormonal levels, psychological status, medication, and HIV disease progression concerning sexual functioning in HIV-positive men.
Main Methods:
- Fifty HIV-positive men completed the Derogatis Sexual Functioning Inventory (DSFI).
- Serum hormonal assays were performed, including testosterone, thyroid function tests, luteinizing hormone, prolactin, and estradiol.
- Participants were categorized based on symptomatic or asymptomatic HIV/AIDS status.
Main Results:
- All participants reported some degree of sexual dysfunction.
- Symptomatic HIV/AIDS patients exhibited more negative mood, lower sexual satisfaction, and poorer body image compared to asymptomatic individuals.
- Asymptomatic HIV patients generally maintained normal testosterone levels, unlike symptomatic patients.
Conclusions:
- Sexual dysfunction is prevalent in men with HIV and increases with symptomatic disease progression to AIDS.
- Both physiological factors, such as low testosterone, and psychological issues significantly impact sexual health in this population.
- No correlation was found between medications and low testosterone levels in this cohort.
Abstract:
Sexual functioning is often neglected in the care of HIV-infected patients. Little information exists about the relationship between hormonal factors, psychological factors, medication, HIV disease stage and sexual functioning among persons with HIV disease. In this study, 50 HIV+ men completed the Derogatis Sexual Functioning Inventory (DSFI), and had serum hormonal assays drawn (testosterone, thyroid function test, leuteinizing hormone, prolactin and oestradiol). Although all the subjects reported some degree of sexual dysfunction, persons with symptomatic HIV/AIDS reported more negative mood, lower sexual satisfaction scores and worse body image than persons with asymptomatic HIV. Persons with asymptomatic HIV also tended to have normal testosterone levels compared with persons with symptomatic HIV/AIDS. No relationship was found between medications and low testosterone, although numbers were small. These results suggest that sexual dysfunction is prevalent among persons with HIV disease, is more common as patients become symptomatic and progress to AIDS and that both physiological (low testosterone) and psychological issues play a role.
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