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Helicobacter pylori infection in immunized mice lacking major histocompatibility complex class I and class II
J Pappo1, D Torrey, L Castriotta
1Mucosal Immunology, Astra Research Center Boston, Inc., Cambridge, Massachusetts 02139, USA. jack.pappo@arcb.us.astra.com
Infection and Immunity
|December 24, 1998
Abstract:
The role of major histocompatibility complex (MHC) class I- and class II-restricted functions in Helicobacter pylori infection and immunity upon oral immunization was examined in vivo. Experimental challenge with H. pylori SS1 resulted in significantly greater (P