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Updated: Jul 28, 2026

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat
Published on: October 29, 2014
Virulence properties of Escherichia coli 83972, a prototype strain associated with asymptomatic bacteriuria
R A Hull1, D C Rudy, W H Donovan
1Department of Microbiology and Immunology, Baylor College of Medicine, University of Texas Health Science Center, Houston, Texas, USA. rhull@bcm.tmc.edu
Abstract:
Little is known about bacteria associated with asymptomatic bacteriuria (ABU) with regard to urinary tract colonization mechanisms. In this study, virulence properties of Escherichia coli 83972, a strain that was isolated from a clinical ABU episode, were examined. The genetic potential for expression of P and type 1 pili was demonstrated, and DNA sequences related to type 1C and G (UCA) pilus genes were also detected. However, E. coli 83972 did not express D-mannose-resistant or D-mannose-sensitive hemagglutination after growth under standard conditions in vitro or upon isolation from the urine of colonized test subjects. Limited uroepithelial cell adherence was observed in vivo, and weak D-mannose-sensitive hemagglutination was detected after extended growth in urine in vitro.
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