[Clinical trial of domestic drug polyoxidonium in secondary immunodeficiency]

A M Borisova, L V Laktionova, N Kh Setdikova

|December 29, 1998

Abstract

Aim:

To test clinical efficiency and immunocorrectives characteristics of polyoxidonium in patients with chronic bronchitis (CB) and chronic recurrent furunculosis.

Materials And Methods:

56 patients entered the trial; 13 with CB in remission, 22 with CB in exacerbation and 21 with chronic recurrent furunculosis. Clinical examinations and tests were made before polyoxidonium therapy and 2-3 days after it. Immunological tests consisted of determination of sub-population composition of peripheral blood lymphocytes, serum immunoglobulins and phagocytic activity of neutrophils.

Results:

Polyoxidonium is an effective and safe immunocorrector. It has a strong influence on functional activity of blood phagocytic cells.

Conclusion:

Polyoxidonium treatment of CB and chronic recurrent furunculosis results in positive shifts in hematological and immunological indices. This allows to recommend it for treatment of acute and chronic infections.

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[Clinical trial of domestic drug polyoxidonium in secondary immunodeficiency]

Aim:

Materials And Methods:

Results:

Conclusion:

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