Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Using autoclaved spongiosa]

E H Kuner1, W Schlickewei, M Huber-Lang

  • 1Abteilung Unfallchirurgie, Chirurgische Universitätsklinik Freiburg.

Der Unfallchirurg
|December 29, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Natural killer cells and regulatory T cells in aneurysmal subarachnoid hemorrhage in peripheral blood and cerebrospinal fluid - a pilot study.

Fluids and barriers of the CNS·2026
Same author

[Registry Research Funding of the German Society of Plastic, Reconstructive and Aesthetic Surgery (DGPRÄC) and Research Funding Report 2021/2022].

Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V...·2023
Same author

[Registry Research Funding of the German Society of Plastic, Reconstructive and Aesthetic Surgeons (DGPRÄC) and Research Funding Report 2019/2020].

Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V...·2020
Same author

Crucial role of the terminal complement complex in chondrocyte death and hypertrophy after cartilage trauma.

Osteoarthritis and cartilage·2020
Same author

[The "safe" flap - Preoperative perforator-mapping and intraoperative perfusion assessment to reduce flap-associated morbidity - Consensus statement of the German Speaking Working Group for Microsurgery of the Peripheral Nerves and Vessels].

Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V...·2019
Same author

[Breast pain and fever in a 46-year-old immunosuppressed patient with breast implants].

Der Internist·2019
Same journal

[3D printing in fracture treatment : Current practice and best practice consensus].

Der Unfallchirurg·2022
Same journal

[3D printing in trauma surgery : Germany lags far behind].

Der Unfallchirurg·2022
Same journal

[Subtrochanteric fractures].

Der Unfallchirurg·2022
Same journal

[3D printing in the field of shoulder surgery].

Der Unfallchirurg·2022
Same journal

[New assessment recommendations for disability in private accident insurance, part 1 : An interdisciplinary consented approach-Basics].

Der Unfallchirurg·2022
Same journal

[Amputation techniques].

Der Unfallchirurg·2022
See all related articles

Autoclaving allogenic cancellous bone offers a sterile, biocompatible, and osteoconductive bone graft alternative. While biologically inferior to other methods, it proves suitable for select indications, requiring further research into ultrastructural changes.

Area of Science:

  • Biomaterials Science
  • Orthopedic Surgery
  • Tissue Engineering

Context:

  • Transmission of Human Immunodeficiency Virus (HIV) via allogenic bone grafts necessitates reconsidering preservation methods.
  • Existing cryopreservation guidelines are resource-intensive (labor, time, cost).
  • Autoclaving presents a potential alternative for processing allogenic cancellous bone.

Purpose:

  • To evaluate autoclaving as a method for processing allogenic cancellous bone for grafting.
  • To assess the characteristics and suitability of autoclaved cancellous bone for clinical use.
  • To identify areas for further investigation regarding the effects of autoclaving on bone tissue.

Summary:

  • Allogenic cancellous bone, harvested from femoral heads, is cleaned and autoclaved at 134°C and 2.5 atm.

Related Experiment Videos

  • This process removes organic matter, rendering the bone sterile, biocompatible, and osteoconductive, preserving its anorganic architecture.
  • While biologically less effective than autogenic or cryopreserved bone, autoclaved grafts are suitable for specific indications.

    • Impact:

    • Autoclaved cancellous bone provides a readily available, sterile bone graft material.
    • It serves as a viable substitute in selected orthopedic procedures, reducing reliance on more complex preservation methods.
    • Further research is needed to fully understand ultrastructural changes and identify specific proteins affected by autoclaving.