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Published on: May 15, 2020
Epidemiology, risk factors, and management of peripheral vascular disease
S P O'Brien1, L Mureebe, A Lossing
1Department of Surgery, Allegheny University Hospitals, Philadelphia, PA 19102, USA.
Insights
Peripheral vascular occlusive disease involves genetic and lifestyle factors like obesity and diabetes. Managing these risks can prevent surgery, with noninvasive tests crucial for patient assessment.
Area of Science:
- Vascular Medicine
- Cardiovascular Science
- Medical Diagnostics
Background:
- Peripheral vascular occlusive disease (PVOD) has genetic and modifiable risk factors.
- Key contributors include obesity, diabetes, hypertension, and smoking.
- Medical management is crucial for delaying or preventing surgical intervention.
Purpose of the Study:
- To summarize the multifaceted nature of peripheral vascular occlusive disease.
- To highlight the role of medical management in disease progression.
- To emphasize the importance of noninvasive laboratory assessments.
Main Methods:
- Review of established risk factors for PVOD.
- Discussion of medical management strategies.
- Emphasis on the role of angiography in interventions.
- Highlighting noninvasive laboratory tests for assessment.
Main Results:
- PVOD is influenced by both genetic predisposition and lifestyle choices.
- Effective medical management can significantly alter the need for surgery.
- Angiography is a key tool for both diagnosis and intervention.
- Noninvasive laboratory assessments are paramount for pre- and post-operative evaluation.
Conclusions:
- Integrated management of genetic and lifestyle factors is essential for PVOD.
- Noninvasive diagnostics play a critical role in the comprehensive care of PVOD patients.
Abstract:
Peripheral vascular occlusive disease is initiated with a genetic risk factor component compounded by patient-controlled contributions including obesity, diabetes, hypertension, and smoking. Medical management of these factors may delay or obviate surgical intervention. Angiography may be used to perform angioplasty (+/- stents) or to guide various interventional procedures. The major contribution to pre- and post-operative assessment is the noninvasive laboratory.
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