Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prenatal diagnosis using the triple test

G Palka1, P Guanciali Franchi, M Papponetti

  • 1Cattedra di Genetica Umana, Università degli Studi, Chieti.

Minerva Ginecologica
|December 29, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Erratum: Comprehensive analysis of the self-assembled formation of GaN nanowires on amorphous Al<i>x</i>O<i>y</i>:<i>in situ</i>quadrupole mass spectrometry studies (2019<i>Nanotechnology</i><b>30</b>154002).

Nanotechnology·2026
Same author

Neck collar sign: novel sonographic finding in case of labor arrest.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2025
Same author

Correlation between abnormal umbilical vein flow and birth-weight percentile in low-risk term pregnancies: secondary analysis of multicenter prospective study.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2025
Same author

Management and outcome of fetal abdominal cyst in first trimester: systematic review of the literature.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2024
Same author

Association of umbilical vein flow with abnormal fetal growth and adverse perinatal outcome in low-risk population: multicenter prospective study.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2023
Same author

Experimental characterization of gaseous ion beams produced with the advanced ion source for hadrontherapy (AISHa) at 18 GHz.

The Review of scientific instruments·2023
Same journal

High grade cervical intraepithelial neoplasia positive biopsy: the importance of accurate pre-operative workup.

Minerva ginecologica·2021
Same journal

Efficacy and safety of a novel vaginal medical device in recurrent bacterial vaginosis: a multicenter clinical trial.

Minerva ginecologica·2020
Same journal

[Advisory Board Italiano sulla sindrome dell'ovaio policistico (PCOS): dalle osservazioni all'esperienze cliniche sull'uso del mioinositolo (MYO) e dell'acido alfa-lipoico (ALA) per migliorare i quadri della sindrome].

Minerva ginecologica·2020
Same journal

Update on new imaging technologies in sentinel node detection.

Minerva ginecologica·2020
Same journal

Postoperative pelvic dysfunctions associated with the reconstruction of the pelvic floor.

Minerva ginecologica·2020
Same journal

The role of sentinel-node biopsy in ovarian cancer.

Minerva ginecologica·2020
See all related articles

This study evaluated the triple test for prenatal screening in 2,803 pregnant women. The triple test demonstrated a high detection rate for fetal abnormalities, including Down

Area of Science:

  • Maternal-Fetal Medicine
  • Prenatal Diagnostics
  • Genetics

Background:

  • Prenatal screening is crucial for identifying potential fetal abnormalities early in pregnancy.
  • The triple test is a common screening method used to assess risk for certain genetic and developmental conditions.

Purpose of the Study:

  • To evaluate the effectiveness of the triple test in a large cohort of pregnant women.
  • To determine the detection rates for various fetal abnormalities, including Down's syndrome and neural tube defects.

Main Methods:

  • A screening study involving 2,803 pregnant women.
  • Utilized the
  • Main_Results': [
  • The triple test achieved a high overall detection rate (DR) of 91% for fetal abnormalities.

Related Experiment Videos

  • Specific DRs included 87.5% for Down's syndrome (DS) and 85.5% for neural tube defects.
  • Out of 201 women with positive screening, 20 cases (1:10) of fetal abnormalities were detected, with a 6.5% false positive rate.

    • Main Results:

    • The triple test achieved a high overall detection rate (DR) of 91% for fetal abnormalities.
    • Specific DRs included 87.5% for Down's syndrome (DS) and 85.5% for neural tube defects.
    • Out of 201 women with positive screening, 20 cases (1:10) of fetal abnormalities were detected, with a 6.5% false positive rate.

    Conclusions:

    • High detection rates are attributed to accurate gestational age determination via ultrasound and a homogeneous study population.
    • The triple test is an effective screening tool for identifying fetal abnormalities in pregnant women.
    • Accurate dating and population homogeneity are key factors for optimizing prenatal screening performance.