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[Therapy for intracranial lesions by gamma knife]
1Department of Neurosurgery, Xiangya Hospital, Hunan Medical University, Changsha.
Summary
Gamma knife (GK) radiosurgery effectively treated 281 patients with intracranial lesions, improving quality of life and prolonging survival for those with malignant brain tumors.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Oncology
Context:
- Review of 281 patients with intracranial lesions treated between September 1995 and September 1996.
- Analysis of patient demographics including age and gender distribution.
- Inclusion of follow-up data for a subset of patients.
Purpose:
- To evaluate the efficacy of gamma knife (GK) radiosurgery for intracranial lesions.
- To assess the impact of GK treatment on patient quality of life and survival.
- To analyze changes in tumor volume and lesion diameter post-treatment.
Summary:
- Gamma knife (GK) radiosurgery was applied to 281 patients (170 males, 111 females; age 5-85 years) with intracranial lesions.
- Average Karnofsky Performance Status improved from 70.8 pre-operation to 83.9 post-operation.
- Average tumor volume decreased from 17.1 cm³ to 13.6 cm³, and lesion diameter reduced from 2.8 cm to 2.4 cm.
Impact:
- GK radiosurgery demonstrated significant improvements in patient quality of life.
- The treatment prolonged survival for patients with malignant intracranial tumors.
- This study highlights GK radiosurgery as a valuable therapeutic option for brain tumors.