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Related Experiment Videos

Medically induced gingival hyperplasia

S J Meraw1, P J Sheridan

  • 1Department of Dental Specialties, Mayo Clinic Rochester, MN 55905, USA.

Mayo Clinic Proceedings
|December 30, 1998
PubMed
Summary

Gingival hyperplasia, a side effect of certain medications like phenytoin, can impact oral functions. Good oral hygiene and dental referrals are key to managing this common drug-induced overgrowth.

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Area of Science:

  • Pharmacology
  • Periodontology
  • Oral Medicine

Background:

  • Drug-induced gingival hyperplasia is a frequent adverse effect.
  • Phenytoin, cyclosporine, and calcium channel blockers are commonly implicated medications.
  • Gingival overgrowth can impair speech, mastication, and aesthetics.

Purpose of the Study:

  • To review medications associated with gingival hyperplasia.
  • To provide recommendations for managing drug-induced gingival overgrowth.
  • To highlight the importance of physician and dental practitioner collaboration.

Main Methods:

  • Literature review of medications causing gingival hyperplasia.
  • Discussion of clinical presentation and management strategies.
  • Emphasis on oral hygiene and professional dental care.

Main Results:

  • Identified key medications (phenytoin, cyclosporine, calcium channel blockers) linked to gingival overgrowth.
  • Highlighted the role of inflammation in disease severity.
  • Stressed the importance of early recognition and referral.

Conclusions:

  • Effective management requires awareness of causative medications.
  • An optimal oral hygiene program can mitigate overgrowth severity.
  • Interdisciplinary care involving physicians and dentists is crucial for prevention and management.

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