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Inflammatory response to cardiopulmonary bypass
1Division of Cardiothoracic Surgery, Hospital of the University of Pennsylvania, Philadelphia 19104, USA.
The Annals of Thoracic Surgery
|December 30, 1998
Abstract:
This article reviews the roles of the contact and complement systems and of neutrophils and monocytes in the inflammatory response to cardiopulmonary bypass and open heart operation. These blood proteins and cells, together with other blood elements, produce the vasoactive and cytotoxic substances and microemboli that cause the morbidity associated with cardiopulmonary bypass and open heart operation.