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An Optimized Hemagglutination Inhibition (HI) Assay to Quantify Influenza-specific Antibody Titers
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A 5-year surveillance study of 44,691 isolates of Haemophilus influenzae project Beta-Alert 1993-1997

A Derecola1, D L Butler, R L Kaplan

  • 1Department of Anti-Infectives, SmithKline Beecham Pharmaceuticals, Collegeville, Pennsylvania 19426-0989, USA. ann_m_derecola@sbphrd.com

Antimicrobial Agents and Chemotherapy
|December 31, 1998
PubMed

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Influenza

Influenza is an acute, highly communicable viral disease that affects the respiratory tract and is responsible for seasonal epidemics worldwide. Influenza A is the most prevalent type associated with widespread outbreaks and is subtyped based on two surface glycoproteins: hemagglutinin (H) and neuraminidase (N), as in H1N1. These glycoproteins are essential for viral infectivity, transmission, and immune recognition. Transmission occurs primarily through respiratory droplets and contaminated...