Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fibrous cortical defect with bizarre nuclear features

R D Craver1, S Heinrich, J Mirra

  • 1Department of Pathology, Louisiana State University Medical Center, New Orleans, USA.

Annals of Diagnostic Pathology
|December 31, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Combining plant and dairy proteins to enhance the oxidative stability of microencapsulated lipids in spray-dried powders.

Food chemistry·2026
Same author

No legacy effects of severe drought on carbon and water fluxes in a Mediterranean oak forest.

Plant biology (Stuttgart, Germany)·2025
Same author

Laser driven FLASH radiobiology using a high dose and ultra high dose rate single pulse proton source.

Scientific reports·2025
Same author

Education Team Time Out in Oncologic Visceral Surgery Optimizes Surgical Resident Training and Team Communication-Results of a Prospective Trial.

Journal of surgical education·2023
Same author

Perspectives in linear accelerator for FLASH VHEE: Study of a compact C-band system.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)·2022
Same author

General, spinal or regional anaesthesia does not affect strength performance 6 months after ACL reconstruction.

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA·2022
Same journal

Development and clinical application of a histopathology-based pathological scoring system for IgG4-related disease.

Annals of diagnostic pathology·2026
Same journal

Improved prostate cancer grading by incorporating Gleason pattern quantification, invasive cribriform and intraductal carcinoma in the new QUICC-score.

Annals of diagnostic pathology·2026
Same journal

The long-term postoperative course of an intraosseous spindle cell hemangioma of the calcaneus.

Annals of diagnostic pathology·2026
Same journal

Myoepithelioma-like tumor of the vulvar region shows a quiet genome and heterogeneous detectable mechanisms of SMARCB1 inactivation: Integrated analysis of two cases and review of the literature.

Annals of diagnostic pathology·2026
Same journal

Re-evaluation of "Peptic" duodenitis: A review of 622 consecutive duodenal biopsies.

Annals of diagnostic pathology·2026
Same journal

Unusual morphologic features in molecularly defined high-grade sarcomas of the uterus.

Annals of diagnostic pathology·2026
See all related articles

A rare fibrous cortical defect in the femoral neck showed unusual cell features histologically. Close monitoring confirmed no recurrence, suggesting a benign pseudoanaplastic change.

Area of Science:

  • Orthopedic pathology
  • Skeletal radiology
  • Surgical oncology

Background:

  • Fibrous cortical defects (FCDs) are common benign bone lesions.
  • Radiographic features of FCDs are typically well-defined and characteristic.
  • Histological examination can occasionally reveal atypical cellular morphology.

Observation:

  • A femoral neck FCD presented with typical radiographic findings.
  • Histological examination revealed bizarre nuclear features within the FCD.
  • Associated macrophages also exhibited atypical, bizarre features.

Findings:

  • The lesion was diagnosed as a pseudoanaplastic change, likely ischemic or degenerative, within an old FCD.
  • Mitotic activity was notably absent.
  • Close clinical and radiological follow-up was initiated due to uncertain biological behavior.

Related Experiment Videos

Implications:

  • Recognition of pseudoanaplastic changes in benign bone lesions is crucial for accurate diagnosis.
  • Interdisciplinary collaboration aids in managing lesions with uncertain biological potential.
  • This case highlights the importance of correlating radiographic, histological, and clinical findings.