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Long-term experience with an ultrapure individual dialysis fluid with a batch type machine
W Kleophas1, B Haastert, G Backus
1Dialysezentrum Karlstrasse, Düsseldorf, Germany.
Summary
This study shows that a dialysis system used for over 15 years offers high-quality, individualized care. Key findings include a 5-year survival rate of 59.1% and a low incidence of carpal tunnel syndrome, highlighting the importance of dialysate quality.
Area of Science:
- Nephrology
- Clinical Medicine
- Biomedical Engineering
Background:
- Long-term experience with a specific dialysis equipment used for over 15 years.
- Equipment designed for easy individualization of dialysis fluid composition.
- Focus on delivering dialysate of the highest hygienic quality.
Purpose of the Study:
- To evaluate the long-term outcomes and effectiveness of a specific dialysis system.
- To assess patient survival, complication rates, and treatment parameters.
- To highlight the impact of water and dialysate quality on patient health.
Main Methods:
- Retrospective analysis of data from 399 patients from 1971 onwards.
- Kaplan-Meier method for survival probability estimation.
- Calculation of median hospital days, serum albumin, erythropoietin requirement, and antihypertensive treatments.
Main Results:
- Estimated 5-year survival probability of 59.1%; age and IDDM identified as main risk factors.
- Cumulative incidence of carpal tunnel syndrome after 10 years was 7%.
- High serum albumin levels (>4.0 g/dl) in 82% of patients; 65% required no antihypertensive drugs; 39% received erythropoietin.
Conclusions:
- The described dialysis setup enables high-quality, individualized therapy.
- High serum albumin and low carpal tunnel syndrome incidence underscore the significance of water and dialysate quality.
- The system demonstrates sustained efficacy and patient benefit over an extended period.