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A child with a t(11;19)(q14-21;p12) in a pulmonary mucoepidermoid carcinoma
G Stenman1, V Petursdottir, G Mellgren
1Department of Pathology, Göteborg University, Sahlgrenska University Hospital, Sweden.
Virchows Archiv : an International Journal of Pathology
|December 31, 1998
Abstract:
We report on a mucoepidermoid carcinoma (MEC) of the lung in a 6-year-old girl with a t(11;19)(q14-21;p12) as the sole karyotypic abnormality. An apparently identical t(11;19) has been reported previously in a MEC originating from the major and minor salivary glands. Our findings indicate that the t(11;19) is intimately associated with the mucoepidermoid phenotype and may be used as a diagnostic marker for this tumour type.