Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Risk reduction in the intensive care unit

S Saint1, M A Matthay

  • 1Robert Wood Johnson Clinical Scholars Program, University of Washington, Seattle, USA.

The American Journal of Medicine
|December 31, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Endothelial ENaC as a repressor of oxidative stress and a guardian of lung capillary barrier function in bacterial and viral pneumonia.

Frontiers in physiology·2025
Same author

Corticosteroids in adults with acute respiratory distress syndrome and severe pneumonia.

BJA education·2023
Same author

Mesenchymal stem/stromal cell-based therapies for severe viral pneumonia: therapeutic potential and challenges.

Intensive care medicine experimental·2021
Same author

The Michigan Risk Score to predict peripherally inserted central catheter-associated thrombosis.

Journal of thrombosis and haemostasis : JTH·2017
Same author

Protein biomarkers associated with primary graft dysfunction following lung transplantation.

American journal of physiology. Lung cellular and molecular physiology·2017
Same author

Can intersectional innovations reduce hospital infection?

The Journal of hospital infection·2017

Intensive care units can prevent complications like blood clots and infections. Evidence-based guidelines recommend VTE prophylaxis for most patients and specific skin antiseptics for catheter insertions.

Area of Science:

  • Critical Care Medicine
  • Infectious Disease Prevention
  • Patient Safety

Background:

  • Intensive care unit (ICU) patients are susceptible to serious, preventable complications.
  • Key complications include venous thromboembolism (VTE), stress-related upper gastrointestinal bleeding (SUGIB), and vascular catheter-related infections (VCRI).

Purpose of the Study:

  • To review the epidemiology of VTE, SUGIB, and VCRI in ICU patients.
  • To evaluate preventive treatments for these complications.
  • To provide evidence-based recommendations for preventing these adverse events in critical care settings.

Main Methods:

  • Systematic review of English-language literature from MEDLINE and cross-citation.
  • Preference given to recent publications (last 10 years), meta-analyses, and randomized, double-blinded, intention-to-treat clinical trials.

Related Experiment Videos

  • Focus on epidemiological data and efficacy of preventive strategies.

    • Main Results:

    • Prophylaxis against venous thromboembolism is recommended for most ICU patients.
    • Prophylaxis against stress-related upper gastrointestinal hemorrhage may not be needed for patients without respiratory failure or coagulopathy.
    • Chlorhexidine gluconate is the preferred antiseptic for skin disinfection before and during intravascular catheterization.
    • Antimicrobial- or antiseptic-impregnated central venous catheters are recommended for high-risk patients.
    • Catheter replacement should be based on clinical indication, not routine changes.

    Conclusions:

    • Implementing targeted preventive strategies can significantly reduce complications in ICU patients.
    • Recommendations emphasize individualized prophylaxis for VTE and SUGIB.
    • Adherence to best practices for catheter care, including antiseptic use and judicious catheter replacement, is crucial for preventing infections.