Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Efficient scatter modelling for incorporation in maximum likelihood reconstruction

B F Hutton1, V Baccarne

  • 1Department of Medical Physics, Westmead Hospital, Sydney, Australia.

European Journal of Nuclear Medicine
|December 31, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advanced quantitative evaluation of PET systems using the ACR phantom and NiftyPET software.

Medical physics·2022
Same author

Rapid processing of PET list-mode data for efficient uncertainty estimation and data analysis.

Physics in medicine and biology·2016
Same author

Model-based correction for scatter and tailing effects in simultaneous 99mTc and 123I imaging for a CdZnTe cardiac SPECT camera.

Physics in medicine and biology·2015
Same author

Developments in cardiac-specific SPECT imaging.

The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of...·2012
Same author

Design of a novel slit-slat collimator system for SPECT imaging of the human brain.

Physics in medicine and biology·2009
Same author

Evaluation of a low-dose/slow-rotating SPECT-CT system.

Physics in medicine and biology·2008
Same journal

[Not Available].

European journal of nuclear medicine·2016
Same journal

A Window on Latin America.

European journal of nuclear medicine·2016
Same journal

Erratum: Eur J Nucl Med (1999) 26: 686-692.

European journal of nuclear medicine·2016
Same journal

Nuclear medicine in the next decade.

European journal of nuclear medicine·2014
Same journal

Erratum: Impact of attenuation correction on the accuracy of FDG-PET in patients with abdominal tumors: a free-response ROC analysis.

European journal of nuclear medicine·2014
Same journal

(99m)Tc(V)DMSA quantitatively predicts (188)Re(V)DMSA distribution in patients with prostate cancer metastatic to bone.

European journal of nuclear medicine·2014
See all related articles

This study presents an efficient scatter estimation algorithm for single-photon emission tomography (SPET) reconstruction. The method improves clinical applicability by simplifying scatter modeling within ordered subsets expectation maximization (OSEM).

Area of Science:

  • Medical Imaging
  • Nuclear Medicine
  • Image Reconstruction

Background:

  • Accurate scatter modeling is crucial for maximum likelihood reconstruction in single-photon emission tomography (SPET).
  • Existing methods often lack the efficiency required for clinical application.
  • Developing computationally efficient scatter estimation techniques is a key challenge in SPET.

Purpose of the Study:

  • To introduce an efficient algorithm for scatter estimation in SPET.
  • To validate the algorithm's performance using Monte Carlo simulations.
  • To integrate the scatter estimation within the ordered subsets expectation maximization (OSEM) reconstruction algorithm for clinical feasibility.

Main Methods:

  • Developed a simplified scatter model using spatially invariant convolution for constant tissue depths.

Related Experiment Videos

  • Incorporated a space-dependent build-up factor based on measured tissue attenuation.
  • Integrated scatter estimation into OSEM, applying it once after initial iterations and holding it constant for subsequent steps.

    • Main Results:

    • Monte Carlo simulations validated the accuracy of the proposed scatter estimation approach.
    • Estimating scatter once after at least two OSEM iterations (subset size 8) showed minimal change.
    • Complete scatter-corrected reconstruction was achieved in 38 minutes for a realistic thorax phantom.

    Conclusions:

    • The developed algorithm offers an efficient and clinically applicable method for scatter correction in SPET.
    • The approach significantly reduces computational burden without compromising reconstruction quality.
    • This method enhances the feasibility of advanced maximum likelihood reconstruction techniques in routine clinical practice.