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Synthesis and antiviral activity of novel isodideoxy nucleosides with exocyclic methylene
1Laboratory of Medicinal Chemistry, College of Pharmacy, Ewha Womans University, Seoul, Korea.
Bioorganic & Medicinal Chemistry Letters
|January 1, 1999
Abstract:
Novel isodideoxy nucleosides with exocyclic methylene were synthesized starting from L-xylose utilizing anomeric demethoxylation, Wittig reaction and Mitsunobu reaction as key steps and evaluated for antiviral activity.