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Updated: Oct 26, 2026

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins
Published on: August 15, 2017
Lithium and maintenance electroconvulsive therapy
S Gupta1, R Austin, D P Devanand
1Department of Psychiatry, Olean General Hospital, NY 14760, USA.
Abstract:
This clinical report describes the successful use of a combination of lithium carbonate and maintenance electroconvulsive therapy (ECT) in the treatment of severe bipolar depression. The patient was initially taken off the lithium and given a course of ECT with remarkable improvement in symptoms. He subsequently underwent maintenance ECT, during which lithium was restarted without any side effects. Rating scales were used to assess memory, depression, and mental status. This case suggests that the overlap of the two treatments may be especially beneficial when the plan is to taper maintenance ECT while continuing pharmacotherapy.
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