Correcting for verification bias in studies of a diagnostic test's accuracy
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Updated: Sep 29, 2026

Basics of Multivariate Analysis in Neuroimaging Data
Published on: July 24, 2010
1Department of Medicine, Indiana University School of Medicine, Regenstrief Health Center, Indianapolis 46202-2859, USA. azhou@iupui.edu
Abstract:
Standard methods for assessing the accuracy of diagnostic tests require determination of true disease status for each study patient. In practice, some study patients might not have verified disease status. If the decision to verify a patient is influenced by the test result, analysis using only verified cases might lead to biased results, commonly known as verification bias. This paper reviews recent developments in bias-correction methods for studies on the accuracy of diagnostic tests.
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