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Inhibition of lipid peroxidation mediated by indolizines
A I Nasir1, L L Gundersen, F Rise
1Department of Chemistry, University of Oslo, Norway.
Bioorganic & Medicinal Chemistry Letters
|January 5, 1999
Abstract:
Esters, ethers, carbonates and carbamates of 1-indolizinols and azaindolizinols exhibit a profound inhibition of lipid peroxidation in vitro. The antioxidants were prepared by cyclization of pyridines and diazines with diphenylcyclopropenone followed by introduction of the O-substituent.