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Updated: Oct 17, 2026
07:12
Synthesis and Evaluation of a Ruthenium-based Mitochondrial Calcium Uptake Inhibitor
Published on: October 26, 2017
Synthesis and pharmacological evaluation of benzofuran-acetamides as "antineophobic" mitochondrial DBI receptor
Y Liao1, A P Kozikowski, A Guidotti
1Mayo Foundation for Medical Research and Education, Jacksonville, FL 32224, USA.
Bioorganic & Medicinal Chemistry Letters
|January 5, 1999
Abstract:
A sries of novel benzofuran analogues of N,N-di-n-hexyl-2-phenylindole-3-acetamide (5, FGIN-1-27), a potent and highly specific mitochondrial DBI receptor complex ligand, were synthesized by a modified Fischer method and found in vitro and in vivo to be equally potent and selective as FGIN-1-27.
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