Related Experiment Videos
Sialyl Lewis X-polysaccharide conjugates: targeting inflammatory lesions
M Sakagami1, K Horie, K Nakamoto
1Drug Delivery System Institute, Ltd., Chiba, Japan.
Bioorganic & Medicinal Chemistry Letters
|January 5, 1999
Abstract:
A novel system for active targeting of inflammatory lesions has been established. A SLeX-CMPul conjugate (2) showed accumulation that was 2.5-fold higher in inflammatory lesions in vivo than a SLN-CMPul conjugate (4) and 300-fold higher than monovalent SLeX (6).