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Menorrhagia in von Willebrand disease successfully treated with single daily dose tranexamic acid
1Department of Haematology, Royal Group of Hospitals Trust, Belfast, UK.
Abstract:
Four cases of menorrhagia in von Willebrand disease were successfully treated with tranexamic acid given in a single daily dose of 4 g for the first 3-5 days of the menstrual cycle. The pathophysiology and pharmacokinetics are discussed. The apparent improved efficacy and acceptability of this new dosing regime have been highlighted.