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Verrucous carcinoma, then and now
1Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
American Journal of Surgery
|January 5, 1999
Summary
Verrucous carcinoma, a rare tumor, presents distinct clinical and pathological features. This review covers management strategies and etiology, featuring historical cases like President Cleveland's palate surgery.
Area of Science:
- Oncology
- Pathology
- Surgical Oncology
Background:
- Verrucous carcinoma is a distinct clinicopathological entity, first described by Ackerman in 1948.
- This review synthesizes salient features of verrucous carcinoma, emphasizing its clinical presentation and pathological characteristics.
Discussion:
- Two illustrative case reports are presented: one detailing a patient's long-term survival after multiple procedures for multifocal oral verrucous carcinoma, and another recounting President Grover Cleveland's 1893 palate surgery for the condition.
- The discussion encompasses current management paradigms for this uncommon tumor, drawing insights from historical and contemporary cases.
Key Insights:
- Long-term survival is achievable with appropriate management, even in multifocal cases of verrucous carcinoma.
- Historical accounts, such as President Cleveland's surgery, offer unique perspectives on the management of verrucous carcinoma in different eras.
Outlook:
- Future research directions include investigating the etiology of verrucous carcinoma.
- Continued exploration of optimal treatment strategies for verrucous carcinoma is warranted.