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Updated: Aug 5, 2026

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Stretching Short Sequences of DNA with Constant Force Axial Optical Tweezers
Published on: October 13, 2011
Estimating the persistence length of a worm-like chain molecule from force-extension measurements
C Bouchiat1, M D Wang, J Allemand
1LPT, ENS, Laboratoire propre du CNRS, Paris, France.
Biophysical Journal
|January 6, 1999
Abstract:
We describe a simple computation of the worm-like chain model and obtain the corresponding force-versus-extension curve. We propose an improvement to the Marko and Siggia interpolation formula of Bustamante et al (Science 1994, 265:1599-1600) that is useful for fitting experimental data. We apply it to the experimental elasticity curve of single DNA molecules. Finally, we present a tool to study the agreement between the worm-like chain model and experiments.

