The use of beta-cyclodextrin as a pelletization agent in the extrusion/spheronization process
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Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study
Published on: August 15, 2016
A Gazzaniga1, M E Sangalli, G Bruni
1Instituto Chimico Farmaceutico, Università di Milano, Italy. gazza@imiucca.csi.unimi.it
Drug Development and Industrial Pharmacy
|January 7, 1999
Abstract:
The use of beta-cyclodextrin for the preparation of pellets by the extrusion/spheronization process is described for different formulations and processing conditions. Sieve analysis and friability tests were performed to assess the physical and technological characteristics of pellets. Satisfactory products were obtained with beta-cyclodextrin contents up to 90% by weight.
