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Migraine with aura shows gadolinium enhancement which is reversed following prophylactic treatment
1Department of Neurology, Humboldt-Universität, Charité, Berlin, Germany. garnold@neuro.charite.hu-berlin.de
Cephalalgia : an International Journal of Headache
|January 7, 1999
Abstract:
A 26-year-old patient complained of a series of migraine attacks with aura accompanied by slight pleocytosis and gadolinium (Gd-DTPA) enhancement next to the left middle cerebral artery. The migraine attacks and Gd-DTPA enhancement were reversible during prophylactic treatment with flunarizine.
Insights
A young patient experienced migraine with aura, showing brain inflammation and contrast enhancement. Flunarizine treatment reversed these migraine symptoms and imaging findings.
Area of Science:
- Neurology
- Radiology
Background:
- Migraine with aura is a complex neurological condition.
- Cerebral artery inflammation and enhancement can occur in neurological disorders.
Observation:
- A 26-year-old patient presented with recurrent migraine attacks with aura.
- Cerebral imaging revealed slight pleocytosis and gadolinium (Gd-DTPA) enhancement near the left middle cerebral artery.
Findings:
- The patient's migraine attacks and the observed Gd-DTPA enhancement were fully reversible.
- Prophylactic treatment with flunarizine led to the resolution of symptoms and imaging abnormalities.
Implications:
- This case highlights the potential reversibility of migraine-associated imaging findings.
- Flunarizine may be an effective treatment for specific migraine presentations involving inflammatory markers.
- Further research is warranted to explore the link between migraine aura, neuroinflammation, and contrast enhancement.