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Acute hyponatremia in the perioperative period: insights into its pathophysiology and recommendations for management
M Gowrishankar1, S H Lin, J P Mallie
1Department of Pediatrics, University of Alberta, Edmonton, Canada.
Clinical Nephrology
|January 7, 1999
Abstract:
Our purpose is to review the topic of acute postoperative hyponatremia by focusing on pertinent aspects of the physiology of water and solute excretion. Four areas will be highlighted: an examination of the source of addition of electrolyte-free water, an exploration of the basis for the very large natriuresis that occurs during cerebral salt wasting following neurosurgery, possible reasons to explain why acute postoperative hyponatremia may pose a greater risk for young women [Ayus and Arieff 1996, Ayus et al. 1992, Arieff 1986, Wijdick et al. 1991], and issues related to treatment of acute hyponatremia.