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Acral lentiginous melanoma

E S Harmelin1, R N Holcombe, J P Goggin

  • 1South Miami Hospital Podiatric Residency Program, Fl, USA.

The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons
|January 8, 1999
PubMed
Summary

Acral lentiginous melanoma (ALM) is an aggressive skin cancer found on the hands and feet. Early detection and complete surgical removal are crucial for effective treatment of this malignant tumor.

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Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • Acral lentiginous melanoma (ALM) is a rare but aggressive form of cutaneous melanoma.
  • It characteristically affects the acral skin, including the palms, soles, and digits.
  • ALM often presents with delayed diagnosis due to its location and variable appearance.

Observation:

  • Lesions typically appear as rapidly spreading, darkly pigmented patches.
  • Pigmentation can vary, potentially mimicking benign conditions.
  • Metastatic potential is high, with common sites including the CNS, liver, lungs, bone, and lymph nodes.

Findings:

  • This review synthesizes current literature on ALM.
  • An illustrative case of lower extremity ALM is presented.

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  • The aggressive nature and metastatic potential of ALM are highlighted.

    • Implications:

    • Emphasizes the critical need for early recognition of ALM.
    • Highlights the importance of complete surgical excision with clean margins for treatment.
    • Underscores the necessity of prompt diagnosis and management to improve patient outcomes for this aggressive melanoma.