Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[HHV-8 related diseases]

V Calvez1, P Bossi

  • 1Dpt de Virologie CERVI, Hôpital de la Pitié-Salpêtrière, Paris.

Presse Medicale (Paris, France : 1983)
|January 8, 1999
PubMed
Summary
This summary is machine-generated.

Human herpesvirus 8 (HHV-8) is linked to Kaposi's sarcoma and other cancers. HHV-8 DNA is found in Kaposi lesions and associated with lymphomas and other rare diseases.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A prospective study with Comprehensive Geriatric Assessment (CGA) before curative treatment in older patients with locally advanced head and neck squamous cell carcinoma (LA-HNSCC).

Oral oncology·2026
Same author

ESMO adaptation of Lines of Systemic Therapy (EnLiST): a consensus framework for standardising the designation of lines of therapy in solid tumours.

Annals of oncology : official journal of the European Society for Medical Oncology·2026
Same author

The microbiome in head and neck squamous cell carcinoma: Biological drivers, therapeutic interactions, and emerging clinical applications.

Critical reviews in oncology/hematology·2026
Same author

A multiomic framework for predicting laryngo-esophageal dysfunction following induction chemotherapy in hypopharyngeal-laryngeal carcinoma.

ESMO open·2025
Same author

Validation of a prognostic nomogram for locally advanced oropharyngeal carcinoma treated with intensity-modulated radiotherapy with/without systemic therapy.

ESMO open·2025
Same author

Sinonasal malignancy: ESMO-EURACAN Clinical Practice Guideline for diagnosis, treatment and follow-up.

ESMO open·2025

Area of Science:

  • Oncology
  • Virology
  • Pathology

Context:

  • Kaposi's sarcoma (KS) is an AIDS-defining illness.
  • KS is associated with human herpesvirus 8 (HHV-8).
  • The role of HHV-8 in other diseases is under investigation.

Purpose:

  • To summarize the association of HHV-8 with Kaposi's sarcoma.
  • To explore the link between HHV-8 and other malignancies.

Summary:

  • HHV-8 DNA sequences are detected in all epidemiological forms of Kaposi's disease.
  • A direct correlation exists between HHV-8 infection, peripheral blood mononuclear cells (PBMC), and KS development.
  • HHV-8 is found in spindle and endothelial cells within Kaposi lesions.
  • HHV-8 is implicated in body-cavity-based lymphomas and Castleman's disease.

Related Experiment Videos

  • A potential association between HHV-8 and multiple myeloma, kidney transplant-associated epithelial tumors, angiosarcoma, and angiolymphoid hyperplasia is suggested.

    • Impact:

    • Establishes HHV-8 as a key etiological agent in Kaposi's sarcoma.
    • Highlights HHV-8's broader oncogenic potential in various cancers.
    • Informs diagnostic and therapeutic strategies for HHV-8-associated conditions.