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A Protocol for Analyzing Hepatitis C Virus Replication
Published on: June 26, 2014
TOFE human-B-cell-line-based adsorption-inhibition assay to detect HCV neutralizing antibodies
M B Valli1, L Bertolini, A Manzin
1Istituto di Medicina Sperimentale, Rome, Italy.
Research in Virology
|January 8, 1999
Abstract:
We previously demonstrated that the human lymphoblastoid B-cell line (LCL) TOFE, derived from normal human bone marrow, is permissive to HCV infection. In this report we developed an in vitro HCV adsorption-inhibition assay based on TOFE cells, to reveal the presence of neutralizing antibodies in sera from acutely infected patients.
