Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Peripheral vascular deficit in leprosy

S Kaur, P L Wahi, R N Chakravarti

    International Journal of Leprosy and Other Mycobacterial Diseases : Official Organ of the International Leprosy Association
    |July 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A rheumatic fever and rheumatic heart disease control programme in a rural community of north India.

    The National medical journal of India·2018
    Same author

    Pericardial effusion following esophageal variceal sclerotherapy.

    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology·2006
    Same author

    Prediction of novel and analogous folds using fragment assembly and fold recognition.

    Proteins·2005
    Same author

    Prediction and functional analysis of native disorder in proteins from the three kingdoms of life.

    Journal of molecular biology·2004
    Same author

    Omeprazole as adjuvant therapy to endoscopic combination injection sclerotherapy for treating bleeding peptic ulcer.

    The American journal of medicine·2001
    Same author

    Lectin mediated binding of Streptococcus pyogenes to human oropharyngeal mucosal epithelial cells.

    Indian journal of experimental biology·1996

    Vascular lesions are common in leprosy patients, affecting over half of those studied. These vascular changes in the hands and feet likely contribute to the characteristic deformities seen in leprosy.

    Area of Science:

    • Vascular Medicine
    • Infectious Diseases
    • Dermatology

    Background:

    • The role of vascular lesions in leprosy pathogenesis remains controversial.
    • Leprosy can cause significant deformities, particularly in the extremities.

    Purpose of the Study:

    • To investigate the frequency and nature of vascular abnormalities in leprosy patients.
    • To determine if vascular changes correlate with leprosy-induced deformities.

    Main Methods:

    • Brachial and posterior tibial arteriography performed on 35 leprosy patients under 40.
    • Histopathological analysis of vascular tissue from patients and controls.
    • Assessment of skin thermometry and reflex vasodilatation.

    Main Results:

    Related Experiment Videos

    • Arteriographic abnormalities were observed in 50% of wrist/palm vessels and 75-94% of digital vessels.
    • The ulnar artery (74%) was more affected than the radial artery (50%).
    • Histological changes were noted in nearly half of the patients' vessels; impaired reflex vasodilatation was common.

    Conclusions:

    • Vascular involvement in leprosy is frequent and significant.
    • These vascular changes likely play a crucial role in the development of hand and foot mutilations in leprosy.