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Endogenous opiates: 1997

G A Olson1, R D Olson, A L Vaccarino

  • 1Department of Psychology, University of New Orleans, LA 70148, USA.

Peptides
|January 8, 1999
PubMed
Summary
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This review covers 1997 research on the behavioral effects of opiate peptides and antagonists, excluding pure analgesia. It details findings on stress, addiction, mood, and neurological functions related to the opiate system.

Area of Science:

  • Neuroscience
  • Pharmacology
  • Behavioral Science

Background:

  • The opiate system plays a crucial role in regulating various physiological and behavioral processes.
  • Annual reviews are essential for synthesizing the rapidly evolving research in this field.

Purpose of the Study:

  • To summarize research published in 1997 on the behavioral effects of opiate peptides and antagonists.
  • To provide a comprehensive overview of the opiate system's influence on diverse functions, excluding purely analgesic effects.

Main Methods:

  • Literature review and synthesis of studies published in 1997.
  • Categorization of research findings based on behavioral and physiological domains.

Main Results:

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  • Opiate system research in 1997 explored its influence on stress, tolerance, dependence, and substance use (alcohol).
  • Significant findings were reported regarding the opiate system's role in mood regulation, learning, memory, reward, and cardiovascular and respiratory functions.
  • The review also covered the opiate system's impact on gastrointestinal, renal, hepatic, immunologic, and developmental processes, as well as neurological disorders and general activity.

    • Conclusions:

    • The opiate system is a complex modulator of a wide array of behaviors and physiological functions.
    • Continued research is vital for understanding the multifaceted roles of opiate peptides and antagonists in health and disease.