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Updated: Aug 15, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
Perforation during gas reduction of intussusception
1Department of Paediatric Surgery, Christchurch Hospital, Private Bag 4710, Christchurch, New Zealand.
Insights
Gas enema reduction for intussusception carries a 1.1% perforation risk in infants. Prompt recognition and intervention, such as paracentesis, are crucial for managing this respiratory distress complication.
Area of Science:
- Pediatric Gastroenterology
- Abdominal Imaging
- Surgical Complications
Background:
- Intussusception is a common pediatric surgical emergency.
- Gas enema reduction is a frequently used therapeutic modality.
- Perforation is a known but infrequent complication of gas enema reduction.
Purpose of the Study:
- To determine the incidence of perforation during gas enema reduction of intussusception.
- To identify risk factors and clinical features associated with perforation.
- To describe the management and outcomes of perforation during gas enema reduction.
Main Methods:
- Retrospective review of 650 consecutive attempted gas enemas for intussusception.
- Analysis of clinical data, radiologic findings, and procedural outcomes.
- Case series review of 7 children who sustained perforation during gas enema.
Main Results:
- Perforation occurred in 7 infants (1.1%) during gas enema reduction.
- Pneumoperitoneum led to rapid abdominal distension and acute respiratory distress in affected infants.
- All perforated cases showed prior radiologic evidence of bowel obstruction and a longer symptom history.
- No perforations occurred during delayed repeat enema reductions.
- Perforation resulted in minimal peritoneal contamination, with no identified pathological lead point.
Conclusions:
- Gas enema reduction for intussusception has a low but significant risk of perforation.
- Early recognition of pneumoperitoneum and prompt intervention are vital for managing respiratory distress.
- Patients with pre-existing bowel obstruction and prolonged symptoms may be at higher risk.
- Delayed repeat enemas appear safe, and perforations cause minimal contamination.
Abstract:
Perforation during attempted gas-enema reduction of intussusception is more common than during a barium enema. In a review of 650 consecutive attempted gas enemas, perforation occurred in 7 infants (1.1%). Gross abdominal distension from the pneumoperitoneum may be rapid and cause splinting of the diaphragm, which leads to acute respiratory distress. This complication is readily recognised at the time of the gas enema, and may require immediate intervention by paracentesis using a 14-gauge needle. A review of 7 children with intussusception in whom perforation occurred revealed that all had radiologic evidence of bowel obstruction (air-fluid levels) prior to the enema, and the patients had had a relatively long history since the onset of symptoms. No perforation occurred during a delayed repeat enema reduction. Perforation during gas enema produces minimal peritoneal contamination. No pathological lesion at the lead point of the intussusception was identified in any of the children in whom perforation occurred.
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