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Updated: Aug 14, 2026

Vascular Balloon Injury and Intraluminal Administration in Rat Carotid Artery
Published on: December 23, 2014
Percutaneous intentional extraluminal (subintimal) recanalization of crural arteries
1Department of Radiology, Leicester Royal Infirmary NHS Trust, Infirmary Close, UK.
Insights
Subintimal angioplasty is a safe and effective minimally invasive treatment for critical limb ischaemia (CLI) caused by blocked crural arteries. This procedure offers a cost-effective alternative to surgery, especially for elderly and frail patients.
Area of Science:
- Vascular Surgery
- Interventional Radiology
Background:
- Critical limb ischaemia (CLI) frequently involves occlusive disease of the crural arteries.
- Minimally invasive treatments for CLI should focus on recanalizing these occluded arteries.
Purpose of the Study:
- To evaluate the safety and effectiveness of subintimal angioplasty for long occlusions in crural arteries.
Main Methods:
- Subintimal angioplasty was performed on patients with CLI due to long occlusions of crural arteries.
Main Results:
- The procedure was found to be safe and effective.
- It provides an alternative to reconstructive surgery.
Conclusions:
- Subintimal angioplasty is a viable and cost-effective treatment for CLI in suitable patients.
- This minimally invasive approach is particularly beneficial for elderly and frail individuals.
Abstract:
Patients with critical limb ischaemia (CLI) often have occlusive disease of the crural arteries. Therefore attempts at treating CLI by minimally invasive means has to be directed towards recanalization of occluded crural arteries. Subintimal angioplasty of long occlusions of the crural arteries is safe and effective and is therefore an excellent alternative to reconstructive surgery in patients who are frequently elderly and frail. It is also relatively cheap when compared to bypass surgery.
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