Related Experiment Videos
[Factors related with compliance with tuberculosis chemoprophylaxis]
F Galvañ Olivares1, C Santiuste de Pablos
1Centro de Prevención y Control de la Tuberculosis, Consejería de Sanidad y Política Social de Murcia.
Objectives:
To determine therapeutic tolerance and compliance level with antituberculous chemoprophylaxis.
Patients And Methods:
587 patients were proposed for antituberculous chemoprophylaxis with isoniazid from January 1995 to June 1996 in Murcia (Spain).
Results:
3.6% of the patients gave up treatment because of hepatic intolerance and 73% completed the prophylaxis. Non-compliance related factors were: social risk factors (odds ratio [OR] = 9.31), previous history of allergies (OR = 2.87), previous personal history of tuberculosis-related events (OR = 0.49) and interaction between sex and age.
Conclusions:
Support and intervention measures directed to risk groups of a social origin deem to be needed. Control measures and information provided to middle-aged males, with particular emphasis to the first weeks of prophylaxis, should also be implemented.