Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Irritable bowel syndrome symptom patterns: frequency, duration, and severity

B Hahn1, M Watson, S Yan

  • 1Glaxo Wellcome, Research Triangle Park, North Carolina 27709-3398, USA.

Digestive Diseases and Sciences
|January 9, 1999
PubMed
Summary

Irritable bowel syndrome (IBS) is chronic, with most patients experiencing daily symptoms like pain and bloating. Symptoms often occur sequentially, not simultaneously, impacting quality of life.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction to: Tooth discoloration induced by apical plugs with hydraulic calcium silicate-based cements in teeth with open apices-a 2-year in vitro study.

Clinical oral investigations·2025
Same author

In vitro validation of colon delivery of vitamin B2 through a food grade multi-unit particle system.

Beneficial microbes·2024
Same author

Biomechanical parameters of the golf swing associated with lower back pain: A systematic review.

Journal of sports sciences·2024
Same author

Influence of the Scalpel Finishing Technique on Marginal Gap Formation in Class II Resin Composite Restorations.

Operative dentistry·2022
Same author

A systematic review and meta-analysis of global and social functioning among people at risk of bipolar disorder.

Journal of affective disorders·2022
Same author

<i>In situ</i> evaluation of contact stiffness in a slip interface with different roughness conditions using ultrasound reflectometry.

Proceedings. Mathematical, physical, and engineering sciences·2022

Area of Science:

  • Gastroenterology
  • Clinical Medicine
  • Patient-Reported Outcomes

Background:

  • Irritable bowel syndrome (IBS) is a prevalent chronic gastrointestinal disorder.
  • Understanding IBS symptom patterns is crucial for effective patient management.

Purpose of the Study:

  • To investigate the frequency, duration, severity, and episodic patterns of IBS symptoms in adult patients.
  • To characterize the daily experience of IBS symptoms over a 12-week period.

Main Methods:

  • A 12-week prospective study involving 122 adult IBS patients across the US, UK, and Netherlands.
  • Daily symptom reporting via an interactive telephone data entry system.
  • Analysis of data from 59 patients who met the 70-day reporting criteria.

Related Experiment Videos

Main Results:

  • The majority of patients reported at least one IBS symptom on over 50% of study days.
  • Individual symptoms like pain/discomfort (33%), bloating (28%), and altered stool (25%) occurred frequently but often sequentially.
  • Symptom episodes averaged 12.4 over 12 weeks, with moderate severity for most symptoms.

Conclusions:

  • IBS is characterized by chronic, often sequential, symptom occurrence.
  • The daily symptom burden and episodic nature of IBS highlight its significant impact on patients' lives.
  • Further research can inform better therapeutic strategies for managing IBS chronicity.