Related Experiment Video
Updated: Aug 9, 2026

Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention
Published on: October 16, 2013
Abstract:
In the nineteenth century, introduction of the first inhaled general anaesthetic (Long, 1842) induced a further search for new types of anaesthesia: carbon dioxide, petroleum ether, derivatives of ethylene, acetone, methyl dichloride, and the study of a new technique-hypnosis. Only chloroform, ether, nitrous oxide were used. Towards the end of the century, ether became the mainstay of inhaled anaesthetics. The other routes of administering anaesthetics (rectal, venous, spinal, local) appeared around 1860.
More Related Videos
14:52Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers
Published on: January 13, 2018
08:16Optogenetic Activation of Afferent Pathways in Brain Slices and Modulation of Responses by Volatile Anesthetics
Published on: July 23, 2020
Related Concept Videos
Local Anesthetics: Chemistry and Structure-Activity Relationship
Local Anesthetics: Clinical Application as Spinal Anesthesia
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Stages of General Anesthesia
Parenteral Anesthetics: Overview
Inhalational Anesthetics: Overview