Related Experiment Video
Updated: Jul 19, 2026

Examining the Characteristics of Episodic Memory using Event-related Potentials in Patients with Alzheimer's Disease
Published on: August 30, 2011
Spoken word recognition in individuals with dementia of the Alzheimer's type: changes in talker normalization and
1Department of Psychology, Washington University, St. Louis, Missouri 63130, USA. msommers@artsci.wustl.edu
Abstract:
Four experiments were conducted to examine the effects of dementia of the Alzheimer's type (DAT) on talker normalization and lexical discrimination. Talker normalization has been proposed as the principal mechanism underlying listeners' ability to maintain perceptual constancy for speech signals. Lexical discrimination refers to the ability to distinguish individual words from phonetically similar items stored in the mental lexicon. Healthy older adults served as controls. Comparisons of controls and very mildly impaired patients with DAT revealed no significant change in either lexical discrimination or talker normalization. In contrast, individuals with more advanced DAT (mildly demented) exhibited significant declines in both abilities. The results are discussed with respect to the possible roles of general slowing and inhibitory declines as factors affecting speech perception in DAT.
More Related Videos
06:48Lexical Decision Task for Studying Written Word Recognition in Adults with and without Dementia or Mild Cognitive Impairment
Published on: June 25, 2019
05:48Memorization-Based Training and Testing Paradigm for Robust Vocal Identity Recognition in Expressive Speech Using Event-Related Potentials Analysis
Published on: August 9, 2024
Related Concept Videos
Alzheimer's Disease: Overview
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
Alzheimer's Disease: Treatment
Dementia
The progression of dementia is generally gradual.
Alzheimer Disease l: Introduction
Alzheimer Disease ll: Pathophysiology
Dementia l: Introduction