Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Miliary tuberculosis]

H Nagai1, M Mori

  • 1Department of Respiratory Diseases, National Tokyo Hospital.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|January 12, 1999
PubMed
Summary

This retrospective study on miliary tuberculosis found fever, elevated alkaline phosphatase, and chest X-ray nodules are common. Diagnosis relies on cultures and biopsies, with most patients responding to treatment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Interferon-gamma and tumor necrosis factor-alpha protect mice from invasive aspergillosis.

The Journal of infectious diseases·1995
Same author

Genomic aberrations in human hepatoblastomas detected by 2-dimensional gel analysis.

Cancer research·1995
Same author

Effect of some immunosuppressors on allergic bronchial inflammation and airway hyperresponsiveness in mice.

International archives of allergy and immunology·1995
Same author

Nizatidine accelerates gastric emptying of a solid meal in rats.

Digestive diseases and sciences·1995
Same author

[Detection and quantitation of cytomegalovirus DNA in plasma from patients with cytomegalovirus pneumonia].

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases·1995
Same author

[The efficacy of granisetron as a prophylactic anti-emetic agent used in conjunction with MCNU and VP16 chemotherapeutic regimens in the management of a pediatric case of hypothalamic anaplastic astrocytoma].

Gan to kagaku ryoho. Cancer & chemotherapy·1995

Area of Science:

  • Infectious Diseases
  • Pulmonology
  • Radiology

Context:

  • Miliary tuberculosis (TB) is a severe disseminated form of Mycobacterium tuberculosis infection.
  • Early and accurate diagnosis is crucial for effective treatment and improved patient outcomes.
  • Understanding the spectrum of clinical and radiological findings aids in recognizing this challenging condition.

Purpose:

  • To retrospectively analyze the clinical presentation, diagnostic findings, and treatment outcomes of 74 patients with miliary tuberculosis.
  • To identify the most common symptoms, radiological features, and microbiological/biopsy results associated with miliary TB.
  • To evaluate the efficacy of antituberculosis therapy and identify factors associated with mortality.

Summary:

  • Fever (97.3%), elevated serum alkaline phosphatase (67.6%), and nodular chest X-ray findings (98.6%) were the most frequent indicators in 74 miliary TB cases.
  • Mycobacterium tuberculosis was detected in sputum (76.8%) and urine (58.6%), with high positivity rates in bone marrow, lymph node, liver, and lung biopsies.
  • While most patients responded to antituberculosis therapy, seven died, four of whom developed adult respiratory distress syndrome.

Impact:

  • Highlights key diagnostic markers for miliary tuberculosis, aiding clinicians in timely diagnosis.
  • Emphasizes the importance of microbiological and histopathological confirmation in diagnosing disseminated TB.
  • Provides insights into treatment response and potential complications, informing clinical management strategies.

Related Experiment Videos