Related Experiment Video
Updated: Sep 14, 2026

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice
Published on: September 19, 2016
[Recent clinical aspect of tuberculin reaction]
1Department of Pathology, Shimane Medical University.
Abstract:
The tuberculin reaction is the best known and most widely studied form of delayed hypersensitivity and is a clinically acceptable measure of cell mediated immunity. The reaction is characterized by a delayed response to antigenic challenge which is mediated by Th1 cells. This sort of reaction has been thought to form part of the body defenses against a number of infections and infestations. Currently, however, evidence is more favour of a dissociation between allergy and resistance. On the other band it is also evidence that the ability to respond to antimicrobacterial therapy parallel the strength of cell-mediated immune reactivity. Tuberculin test still possess the value as the diagnostic and prognostic parameters for tuberculosis.
Related Concept Videos
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Hypersensitivity Reactions: Delayed Hypersensitivity Reactions
Tuberculosis
Hypersensitivity Reactions: Immune-Complex Reactions

