Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Aids]

H Nagai1

  • 1Department of Respiratory Diseases, National Tokyo Hospital.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|January 12, 1999
PubMed
Summary
This summary is machine-generated.

Tuberculosis and human immunodeficiency virus (HIV) coinfection is rising in Japan. HIV patients often present with extrapulmonary tuberculosis, requiring prompt diagnosis and treatment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Interferon-gamma and tumor necrosis factor-alpha protect mice from invasive aspergillosis.

The Journal of infectious diseases·1995
Same author

Genomic aberrations in human hepatoblastomas detected by 2-dimensional gel analysis.

Cancer research·1995
Same author

Effect of some immunosuppressors on allergic bronchial inflammation and airway hyperresponsiveness in mice.

International archives of allergy and immunology·1995
Same author

Nizatidine accelerates gastric emptying of a solid meal in rats.

Digestive diseases and sciences·1995
Same author

[Detection and quantitation of cytomegalovirus DNA in plasma from patients with cytomegalovirus pneumonia].

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases·1995
Same author

[The efficacy of granisetron as a prophylactic anti-emetic agent used in conjunction with MCNU and VP16 chemotherapeutic regimens in the management of a pediatric case of hypothalamic anaplastic astrocytoma].

Gan to kagaku ryoho. Cancer & chemotherapy·1995
Same journal

[Development of novel therapeutics for multiple myeloma and improvement of drug lag].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[Clinical pharmacy services to patients of immunomodulatory drugs].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[Therapeutic drug monitoring of the new anti-myeloma drugs in the treatment of multiple myeloma].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[Prognostic value of minimal residual disease assessment using next-generation sequencing in multiple myeloma].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[The evaluation of minimal residual disease in multiple myeloma by an allele-specific oligonucleotide real-time PCR].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[Evaluation of minimal residual disease in myeloma by multiparametric flow cytometry].

Nihon rinsho. Japanese journal of clinical medicine·2019
See all related articles

Area of Science:

  • Infectious Diseases
  • Immunology
  • Public Health

Context:

  • Increasing incidence of tuberculosis (TB) and human immunodeficiency virus (HIV) infection in Japan.
  • Mycobacterium tuberculosis (M. tuberculosis) exhibits higher virulence, leading to earlier disease manifestation in early-stage immunodeficiency.
  • Traditionally, reactivation of latent TB is considered the primary cause, but recent exogenous reinfection is increasingly recognized in HIV-infected individuals.

Purpose:

  • To highlight the unique clinical features and pathogenesis of tuberculosis in patients with HIV infection.
  • To discuss the diagnostic challenges and therapeutic considerations for TB/HIV coinfection.
  • To emphasize the importance of early diagnosis and management of TB in the context of HIV.

Summary:

Related Experiment Videos

  • Tuberculosis is more likely to occur earlier in the course of HIV infection due to M. tuberculosis virulence.
  • Extrapulmonary involvement is a hallmark of TB in HIV-infected individuals, often co-occurring with pulmonary disease.
  • Chest X-ray findings in severely immunocompromised patients may include hilar adenopathy, pleural effusions, and miliary patterns.

    • Impact:

    • Improved understanding of TB pathogenesis in HIV patients can lead to better diagnostic strategies.
    • Recognizing the high frequency of extrapulmonary TB can guide clinical suspicion and workup.
    • Effective antituberculosis therapy remains crucial for managing coinfected patients, improving outcomes.