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Solid-phase Synthesis of [4.4] Spirocyclic Oximes
Published on: February 6, 2019
Pharmaceutical development and specification of stereoisomers
R C Williams1, C M Riley, K W Sigvardson
1Pharmaceutical Research and Development, DuPont Merck Pharmaceutical Company, Wilmington, DE 19880, USA.
Abstract:
The pharmaceutical development of chiral drugs requires the activities of many different research and development groups. Guidelines which help to coordinate the activities of these groups and assist in the successful development of compounds with either single or multiple chiral centers are outlined and discussed.
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